Hello everyone,

I have a variable of time (hms) that represents the time a blood sample was drawn. I would like to make a baseline of midnight (or perhaps 00:05 ) so that I can make an analysis of changes in cellular composition from midnight to blood draw. I sense I need to make an interval, but I don't know how to proceed since the baseline for each sample will have different dates, although the same baseline time. Time can be set up as number of minutes since midnight.

Any ideas would be much appreciated.

Some of these functions may help you:

The base case, with individually entered times

```
library(lubridate)
#>
#> Attaching package: 'lubridate'
#> The following objects are masked from 'package:base':
#>
#> date, intersect, setdiff, union
basetime <- ymd_hms("2010-12-13 00:00:00")
drawtime <- ymd_hms("2010-12-13 15:30:30")
elapsed <- drawtime - basetime
elapsed
#> Time difference of 15.50833 hours
```

^{Created on 2020-09-09 by the reprex package (v0.3.0)}

Because `lubridate`

provides functions to access date components, the elapsed variable can be through `hour()`

and `minute()`

.

```
library(lubridate)
#>
#> Attaching package: 'lubridate'
#> The following objects are masked from 'package:base':
#>
#> date, intersect, setdiff, union
basetime <- ymd_hms("2010-12-13 00:00:00")
drawtime <- ymd_hms("2010-12-13 15:30:30")
elapsed <- drawtime - basetime
(hour(drawtime)*60 + minute(drawtime)) / 60
#> [1] 15.5
```

^{Created on 2020-09-09 by the reprex package (v0.3.0)}

```
<sup>Created on 2020-09-09 by the [reprex package](https://reprex.tidyverse.org) (v0.3.0)</sup>
```

Thank you technocrat for your suggested solution. The dataset I received had already separated the date from time, so I have two columns. They are formatted in "hms".

Martin,

I do have the time variable formatted in hms:Pretty Time of Day. I can confirm that the class is hms diff time. I was wondering if I could remove the seconds, so the time would represent the number of minutes since 00:00 ? I have a problem with the large number that represents all those seconds: 1) interpretation of estimates from a linear model, 2) calculation of differential expression. I am hoping that total number of minutes since midnight would be easier to work with.

Thanks for your help.

I think `hms`

requires the seconds to be specified. You can divide the duration by 60 to get the no. of minutes.

Ok, thanks this is what I am thinking. But I need some guidance on how to proceed. If I have a time, for example 09:10:00, how do I convert to a numerical value in order to divide by 60?

I'd use lubridate::time_length().

```
> t1 <- ymd_hms('2020-09-14 12:00:00')
> t2 <- ymd_hms('2020-09-14 13:00:05')
> dur <- t2 - t1
> dur
Time difference of 1.001389 hours
> class(dur)
[1] "difftime"
> time_length(dur, 'second')
[1] 3605
> time_length(dur, 'minute')
[1] 60.08333
> time_length(dur, 'hour')
[1] 1.001389
> ```
```

Thanks so much. I look forward to trying this solution.

Best regards!