Error in if (file.exists(pythonPath)) return(pythonPath) : argument is of length zero

I just updated both R (4.1.2) and RStudio (2021.09.0 Build 351). Don't know if this error is associated with one, the other, or both. See the final line for the error message. I get this message when I double click on an existing .Rproj file. I do not get this message when I launch RStudio from the Start menu. I do not get this message when I launch R from the Start menu (that's why I'm starting here).

R version 4.1.2 (2021-11-01) -- "Bird Hippie"
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Error in if (file.exists(pythonPath)) return(pythonPath) :
argument is of length zero

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