Is up to you, but if I was you I would use the default system level package library.
Incompatibility of R with cloud synced folders is a know issue so setting your package library outside OneDrive could indeed help, although, since you are not providing clear information about your problem I can't be completely sure this by itself is going to solve it.
Well, if you know better than me, then I think I don't have more advice to give you.