No such file or directory, but the file exist!

cpgi.df <- read.table("intro2R_data/data/subset.cpgi.hg18.bed", header = FALSE)
Error in file(file, "rt") : cannot open the connection
In addition: Warning message:
In file(file, "rt") :
cannot open file 'intro2R_data/data/subset.cpgi.hg18.bed': No such file or directory

This is saying R can’t find a file by this name at this directory path.

You can find you current working directly via the getwd function.
https://rdrr.io/r/base/getwd.html

If you’re using RStudio, you can use the handy import dataset tool, which lets you load data via a GUI. It’s also nice since it’ll show you the R code it used to load your data.

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