When you knit an Rmd document the code gets executed in a clean environment other than the one you are currently working on so the mentioned data frame doesn't exist there. You need to include the necessary code to import the data frame into memory, in your Rmd document itself, for example, if the data frame comes from a csv file you would include something like this:
your_data_frame <- read.csv("path_to_file.csv").
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