It depends on what you want to achieve.
In general - why not. That's how most of the services are running in, for example, company I work at. tidyeval makes it quite easy to program over dplyr, so that's not a big issue as well. There is, of course, some bias, but for me piping makes it much easier to understand the flow of the program. And since R is rarely, if ever, used for blazing speed, then adding pipe overhead is never a bottleneck.
So, all in all, I would say that there is nothing stopping you from trying, but it depends a lot on your use-case.