Can't change R Studio preferences: "Error permissions denied"

Hi, I can't change the preferences in Mac RStudio for the last few months. I get the below error when trying to apply or save the preferences. I tried locating the preferences files in ~/Library/Preferences/com.rstudio.desktop.plist and the application file and altering their permissions, and then rebooting RStudio, but that hasn't worked. I also updated RStudio to the latest. Thanks for any tips.

Mac RStudio Version 1.3.1073 / macOS Catalina 10.15.6

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