Error in lm.fit(x, y, offset = offset, singular.ok = singular.ok, ...) : NA/NaN/Inf in 'y'

I'm trying to do a simple logistic regression model on two models. I'm using a ThreeCancers.RData that contains 3 vectors with one of them being GeneExp.

Logistic regression model done with GeneExp$Gene15 as the explanatory variable and y as the response

y such that
yi = 1 if the i-th subject has KIRC cancer and yi = 0 otherwise.
Code for y:

y = as.numeric(CancerType == 'KIRC')

My code for the logistic regression model is:
fit <- lm(log(y) ~ log(GeneExp$Gene15))

However, I keep getting this error that I don't know how to fix. Please help!!

Error in lm.fit(x, y, offset = offset, singular.ok = singular.ok, ...) : **
** NA/NaN/Inf in 'y'

ps. lm works fine w/ these variables without log being added

Are any values in those variables 0? That would throw an error since log(0) is undefined.

1 Like

Is there any to see if there any 0's?

You can use subset(). Here is an example using the mtcars data set where I'm finding all 0 values in the variables vs and am. You can adapt it to your own data.

subset(mtcars, vs == 0 | am == 0)
#>                      mpg cyl  disp  hp drat    wt  qsec vs am gear carb
#> Mazda RX4           21.0   6 160.0 110 3.90 2.620 16.46  0  1    4    4
#> Mazda RX4 Wag       21.0   6 160.0 110 3.90 2.875 17.02  0  1    4    4
#> Hornet 4 Drive      21.4   6 258.0 110 3.08 3.215 19.44  1  0    3    1
#> Hornet Sportabout   18.7   8 360.0 175 3.15 3.440 17.02  0  0    3    2
#> Valiant             18.1   6 225.0 105 2.76 3.460 20.22  1  0    3    1
#> Duster 360          14.3   8 360.0 245 3.21 3.570 15.84  0  0    3    4
#> Merc 240D           24.4   4 146.7  62 3.69 3.190 20.00  1  0    4    2
#> Merc 230            22.8   4 140.8  95 3.92 3.150 22.90  1  0    4    2
#> Merc 280            19.2   6 167.6 123 3.92 3.440 18.30  1  0    4    4
#> Merc 280C           17.8   6 167.6 123 3.92 3.440 18.90  1  0    4    4
#> Merc 450SE          16.4   8 275.8 180 3.07 4.070 17.40  0  0    3    3
#> Merc 450SL          17.3   8 275.8 180 3.07 3.730 17.60  0  0    3    3
#> Merc 450SLC         15.2   8 275.8 180 3.07 3.780 18.00  0  0    3    3
#> Cadillac Fleetwood  10.4   8 472.0 205 2.93 5.250 17.98  0  0    3    4
#> Lincoln Continental 10.4   8 460.0 215 3.00 5.424 17.82  0  0    3    4
#> Chrysler Imperial   14.7   8 440.0 230 3.23 5.345 17.42  0  0    3    4
#> Toyota Corona       21.5   4 120.1  97 3.70 2.465 20.01  1  0    3    1
#> Dodge Challenger    15.5   8 318.0 150 2.76 3.520 16.87  0  0    3    2
#> AMC Javelin         15.2   8 304.0 150 3.15 3.435 17.30  0  0    3    2
#> Camaro Z28          13.3   8 350.0 245 3.73 3.840 15.41  0  0    3    4
#> Pontiac Firebird    19.2   8 400.0 175 3.08 3.845 17.05  0  0    3    2
#> Porsche 914-2       26.0   4 120.3  91 4.43 2.140 16.70  0  1    5    2
#> Ford Pantera L      15.8   8 351.0 264 4.22 3.170 14.50  0  1    5    4
#> Ferrari Dino        19.7   6 145.0 175 3.62 2.770 15.50  0  1    5    6
#> Maserati Bora       15.0   8 301.0 335 3.54 3.570 14.60  0  1    5    8

Created on 2020-05-04 by the reprex package (v0.3.0)

How do I still take a logisitic regression if there are 0's in my variables

There are some workarounds but a lot depends on what those values mean. What is your y variable?