How to do a point-to-point repeated measures analysis of variance along time using the R language

head(data)

A tibble: 6 × 9

组别 编号 姓名 bin time A1B1 A1B2 A2B1 A2B2

1 1 1 litianwei 201 0 0.168 0.118 0.204 0.195
2 1 1 litianwei 202 1 0.168 0.119 0.202 0.194
3 1 1 litianwei 203 2 0.168 0.121 0.202 0.198
4 1 1 litianwei 204 3 0.168 0.124 0.202 0.198
5 1 1 litianwei 205 4 0.167 0.127 0.204 0.202
6 1 1 litianwei 206 5 0.168 0.128 0.205 0.203
I have a data and of this type, where A and B are the independent variables and there is a column of time data, how do I do a repeated measures ANOVA at each time point? That is, how do I do a point-to-point ANOVA along time and output a time range with a p-value less than 0.05?