I have trouble understanding the enrichment score of a GSEA.
I am running DESEQ2 on two groups, ex. control vs treatment. Then, using the output to run a gene set enrichment analysis (clusterprofiler - gseGO).
I get enrichment scores between -1 and +1, which means negative and positive enrichment of specific gene sets.
Is it possible to tell where the difference comes from? Whether a positive enrichment means enrichment in the control or treatment group?