Today I was told that a new RStudio version was available. I promptly installed RStudio (2022.12.0-353) over (2022.07.2-576).
First problem: the location of the executable apparently changed (or the way it is called), so the icon in my panel for launching RStudio did not work anymore. Relatively easy fix, remove the old icon and create a new one.
Second problem: RStudio does not play nicely with sub-architectures anymore. When I want to install/update a package, I immediately get errors along the lines:
/opt/R/R-4.2.2/lib/R/bin/R: line 142: /opt/R/R-4.2.2/lib/R/etc64/ldpaths: No such file or directory
/opt/R/R-4.2.2/lib/R/bin/Rcmd: 39: .: cannot open /opt/R/R-4.2.2/lib/R/etc64/Renviron: No such file
the problem seems to be that in RStudio, I see the following:
> Sys.getenv("R_ARCH")
[1] "64"
If I start R from the command line, I see:
> Sys.getenv("R_ARCH")
[1] "/64"
So I guess until I figure out where in the starting sequence RStudio changes the R_ARCH environment variable, it is back to RStudio (2022.07.2-576) for me. 
I thought I should warn other users who might run an R installation that uses sub-architectures on linux (the only platform on which this is still possible??) about this infidelity.
Cheers,
Berwin
PS: Interestingly, using RStudio (2022.07.2-576), I get the following information:
> Sys.getenv("R_ARCH")
[1] ""
Well, at least it works